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Comparison updated 2 September 2026 · compositions verified on official sources on that date · next re-check: March 2027

Supradyn vs base One: Switzerland's best-known multivitamin, read by a formulator

Supradyn vs base One

Supradyn is the multivitamin everyone knows: supermarket and pharmacy alike. base One is a Swiss formulator's daily base. Verdict first, proof after : every technical term explained as it appears.

Our verdict

Our winner: base One. And plainly: it is our product. Supradyn remains the simple, broad coverage par excellence: practical, everywhere. Our bet is different: fewer label lines, but each in the form the body actually uses. Everything is below to prove us wrong.

The detail few people notice: Supradyn's magnesium is oxide : the least absorbed of common forms : and the iron travels in the same tablet as the zinc.

Easiest to find

Supradyn

everywhere, supermarket to pharmacy

What the body absorbs

base One

active forms: usable without conversion

Useful breadth

base One

29 nutrients, amino acids included

In short, choose:
  • Supradyn if you want broad, familiar coverage without thinking, found everywhere.
  • base One if you want every label line in a form the body uses without converting it.
  • Neither one if a symptom persists or settles in: that is your doctor's job, not a supplement's.
Discover base One

29 nutrients in active forms · one glass a day · reviews published unfiltered

The proof, line by line, below ↓

The key to everything (30 seconds of reading)

Not all vitamins are equal. The same vitamin exists in several chemical versions: its “forms”. Some are active forms: the ones your body uses as-is; others must first be converted, with losses along the way. Systematically choosing active forms, at useful doses, is the orthomolecular approach: the discipline taught by David Giovenco, formulator of base One and president of the International Francophone Academy of Orthomolecular Medicine. Keep this key: the whole comparison reads with it.

What is Supradyn

The historic mainstream multivitamin: 13 vitamins and 9 minerals in one tablet a day (current «Supradyn pro energy-complex» line), built for simple general coverage.

What base One is for

The daily base: covering the essentials every day : 29 vitamins, minerals and amino acids : in active forms (the versions your body uses without converting them), in one pomegranate-flavoured glass. Not a one-off cure: the foundation, day after day.

The comparator, line by line

Green = a form the body uses as-is, or a strength. Amber = a version that must first be converted, or a partial point. Each line says what the nutrient is for.

Vitamin C — defences & collagen
Supradyn
ascorbic acid 180 mg
base One
580 mg
Folate (B9) — cell renewal
Supradyn
folic acid 430 µg
base One
active 5-MTHF 400 µg
Vitamin B12 — nerves & blood formation
Supradyn
cyanocobalamin 3 µg
base One
active forms
Vitamin B6 — energy & neurotransmitters
Supradyn
hydrochloride 4 mg
base One
active P5P
Magnesium — muscles & nerves
Supradyn
oxide 80 mg
base One
citrate 100 mg
Zinc — skin, hair, immunity
Supradyn
citrate 4.4 mg
base One
citrate 5 mg
Selenium — cell protection
Supradyn
mineral selenate 55 µg
base One
L-selenomethionine 55 µg
Iron — oxygen transport
Supradyn
fumarate 8 mg (with the zinc)
Vitamin D3 — bones & immunity
Supradyn
5 µg
What base One adds

The amino acids (750 mg glycine included) and doses above the minimums: what the 6 g powder format allows and no tablet can hold.

What Supradyn adds

Iodine, copper, manganese and molybdenum, plus vitamin D and calcium: real breadth for a single product.

Broad but standard: the Supradyn compromise

Supradyn covers 22 nutrients: its true strength. But look at the forms: magnesium as oxide, B12 as cyanocobalamin, folate as folic acid : the cheapest versions on the market, which the body must first convert. And the iron rides in the same tablet as the zinc: two minerals fighting for the same gut door.

base One bets the other way: every nutrient as the finished molecule : 5-MTHF, active B12, citrates : and deliberately leaves some out (iron, vitamin D) rather than include them in poor conditions.

What Supradyn does well : and its limits, in plain words

Its strengths. Name recognition, universal availability, 22 nutrients including D, iodine and calcium, Bayer's industrial consistency. As the simplest first step, it paved the way for the whole category.

Its limits. The market's cheapest forms (magnesium oxide, cyanocobalamin, folic acid), iron and zinc in the same intake, and no amino acids: a tablet is physically too small.

base One in practice: for whom, when, and what to expect

Who it is for. Adults who want the essentials covered daily without stacking boxes : and especially those who have taken vitamins before and “felt nothing”: often the sign of forms the body used poorly. After 50 or on a plant-based diet, the active B12 in the formula counts double.

When. One glass a day, at the moment that becomes your ritual: morning, or the 5 p.m. alcohol-free apéro. The 90-day course follows the body's own rhythm: skin renews in a month, blood in four.

What to expect, honestly. We promise nothing : here is what biology says. If your diet left gaps : common for magnesium and the B vitamins, which contribute to reducing fatigue : the difference may be felt within weeks. If your intake was already good, base One works silently: it is background coverage, not a stimulant. The honest check-in is at 90 days : and you judge.

What base One does not contain : and why

An honest comparison also lists our absences. They are deliberate:

  • No iron. Iron and zinc use the same entry door of the gut: putting them together makes them hinder each other. A real iron deficiency is measured (ferritin) and corrected in a targeted way. The full explanation.
  • No vitamin D. The right dose depends on your blood status and the season: it varies tenfold between people. One dose for everyone would be either useless or insufficient. Our dedicated article.

Why these choices? base One follows the orthomolecular approach: giving the body molecules it already knows, at useful doses : rather than cheap synthetic versions at minimal doses. It is the discipline practised and taught by David Giovenco, president of the International Francophone Academy of Orthomolecular and Integrative Medicine.

Your questions

Supradyn or Berocca?

Two lines of the same Bayer family: standard forms and reference doses in one, shock doses in the other. This comparison reads for both.

How much per day, and when?

One tablet a day per the maker, rather in the morning. On vitamin timing generally: our dedicated article.

Supradyn or base One?

Depending on your logic: standard, practical, economical coverage : or dosed active forms in the orthomolecular approach. Both honest answers are in the comparator above.

Ready to try the daily base?

29 nutrients in active forms, one glass a day, made in Switzerland : and 5 CHF welcome credit on your first order, applied automatically with your e-mail.

Discover base One

reviews published unfiltered · cancel in one click

Our other comparisonsBurgerstein CELA · Berocca · Burgerstein Multivitamin · AG1 · Centrum · Which magnesium?
DG
David Giovenco · Micronutrition researcher · President, International Francophone Academy of Orthomolecular and Integrative Medicine · Founder & Formulator, nuho

Sources

[1] Official Supradyn pro energy-complex composition, Coop Vitality, recorded 02.09.2026 · [2] Supradyn ingredient list, redcare-apotheke.ch, recorded 02.09.2026 · [3] Walker 2003 · [4] Scaglione & Panzavolta 2014 · [5] base One product page, nuho.ch

This content is published for information purposes and does not replace medical advice. For any health question, talk to your doctor or pharmacist. Compositions recorded on 2 September 2026: report any inaccuracy.

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