Frequently Asked Questions

The nutrient density of fruits, vegetables and grains has dropped 20-80% over 85 years depending on the nutrient. A 2025 optimized diet (varied vegetables, oily fish, legumes, seeds) shows deficits of 19-72% compared to a 1940 farmer's day. Documented in CIQUAL ANSES, Mayer 1997/2022 — independent of individual food choices. Targeted supplementation is no longer optional: it has become structural.

base One is formulated for daily intake. Dosages cover the structural deficits of contemporary diets while staying below EFSA and OSAV tolerable limits. No compound poses a toxic accumulation risk at the recommended dose. During pregnancy, breastfeeding, diagnosed pathology or medication, consult a healthcare professional before supplementation.

Yes, base One fits into a broader protocol. Coherent pairings: omega-3 (EPA/DHA), vitamin D3, coenzyme Q10, polyphenols. Caution with iron: take 4-6 hours apart to avoid DMT1 transporter competition. With added zinc, monitor the zinc/copper balance. With selenium, do not exceed 800 µg/day total.

One base One dose = 6 g of actives, equivalent to 12 standard 500 mg capsules. The powder format integrates 29 bioactive compounds at clinical dosages, impossible to achieve in capsules without multiplying units. Water dissolution also favors progressive absorption and concurrent cellular hydration.

Deliberate scientific choice. Iron, zinc, copper and calcium share the DMT1 intestinal transporter. Administered together in solution, they mutually inhibit each other, reducing absorption by 40-80%. Including them would compromise the entire formula. Vitamin C at 580 mg, however, potentiates non-heme dietary iron absorption: a functional response more effective than direct supplementation.

One 6 g dose dissolves in 500 ml of water at room or cool temperature. Best consumed in the morning before or with breakfast. Morning intake optimizes B-vitamin and magnesium availability throughout the day. For digestive sensitivity, take with meals. Avoid hot water to preserve heat-sensitive bioactive forms.

base One precisely addresses the structural deficits of vegetarian and vegan diets. Vitamin B12 (absent from plants) is provided in its two most bioavailable active forms. Iodine, deficient outside seafood, is covered at 200 µg per dose. Zinc is provided as citrate, high absorption. Vitamin C at 580 mg potentiates non-heme plant iron absorption, functionally compensating for the absence of heme animal iron.

Several axes directly relevant in sport context. L-glutamine at 1,500 mg limits muscle catabolism induced by intense effort and supports gut mucosa integrity. Magnesium and potassium regulate muscle contraction and prevent cramps. B vitamins optimize mitochondrial ATP production. Vitamin C and selenium reduce post-exercise oxidative stress.

base One is particularly suited to conception, pregnancy and breastfeeding phases. Folate as active 5-MTHF is directly assimilable, including for the 30-50% of women with an MTHFR polymorphism: it conditions neural tube closure. Methylcobalamin (B12) supports fetal neurological development. Iodine (200 µg) covers the structural deficit outside seafood. Medical advice remains recommended to personalize the protocol.

Timeframes vary with starting micronutrient status. People with marked deficits may feel improvement from the first doses (fatigue, mental clarity), thanks to the immediate availability of bioactive forms. For moderate deficits, effects build over 1-2 weeks. Three months is the optimal duration to allow cellular renewal and enzymatic regulation processes to express fully.

base One is free of sugar, maltodextrin and artificial excipients. The three auxiliaries each have a documented function: steviol glycosides (sweet perception, zero glycemic index, ~15 mg/dose); citric acid (pH corrector and divalent mineral absorption potentiator); natural fruit-extracted flavor (palatability without synthetic solvent). No ingredient interferes with active compounds.

base One is a complete formula of 29 bioactive compounds — vitamins, minerals, amino acids and organic acid — selected on strict orthomolecular criteria and dosed in synergy. Forms are bioactive (5-MTHF, P-5-P, methylcobalamin, magnesium citrate): the cell receives what the label announces. Low-cost supplements generally use poorly bioavailable forms and sub-clinical doses: only a tiny fraction reaches the cell. Swiss manufacturing, batch-level quality controls.

We currently ship to Switzerland, the EU, the UK, and the USA. We are working on expanding our shipping destinations soon.

Orders placed before 2 PM CET are shipped the same day. Delivery within Switzerland typically takes 1-2 business days. EU orders take 3-5 business days, and international orders take 5-8 business days.

We offer a 30-day satisfaction guarantee. If you are not completely satisfied with your purchase, you can return the unopened box for a full refund within 30 days of purchase. Please contact support@nuho.ch to initiate a return.

Our subscription service ensures you never run out of base One. You'll receive a fresh supply every 30 days at a 15% discount. You can pause, skip, or cancel your subscription at any time from your account portal.

No, there is no minimum commitment. You can cancel immediately after your first order if you wish.