base One: the Swiss multivitamin with 29 bioactive compounds.
Active forms, clinical dosages. Formulated in Neuchâtel by a micronutrition researcher. CHF 1.54 per day.
The multivitamin no one was making. So nuho made it.
For 10 years, David Giovenco formulated dietary supplements for major brands. He saw what no one says out loud: cosmetic dosages to look good on the label, cheap synthetic forms, marketing ahead of science.
base One is what he always wished he could sell. A rigorously formulated powdered multivitamin. Not a miracle promise: a solid 90-day nutritional foundation.
Vitamins
12 essential vitamins in active forms. 5-MTHF (folate), methylcobalamin (B12), P-5-P (B6): directly usable by cells. Energy, nervous system, immunity.
Minerals
Magnesium and potassium in citrate form, highly bioavailable. Muscle regulation, electrolyte balance, nerve function.
Amino acids
L-glutamine, glycine, L-malic acid. Cellular metabolism support, gut mucosa integrity, energy production.
Trace elements
Zinc, selenium, iodine, manganese, chromium. Enzymatic cofactors for immunity, thyroid, antioxidant defense.
Active forms (5-MTHF, P-5-P, methylcobalamin). Clinical doses. No iron or calcium, to avoid DMT-1 antagonisms. See the formulation in detail →
How to use
How to use
Simplicity is consistency.
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01
Measure
1 teaspoon (6g) of powder.
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02
Mix
Dissolve in 3–7 dl of water.
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03
Enjoy
Sip throughout your morning.
29 bioactive compounds. Zero fillers.
*VNR = Valeurs Nutritionnelles de Référence
Formulated by
David Giovenco
Micronutrition Researcher & Educator
Micronutrition researcher, educator, and expert in orthomolecular and cellular medicine. After years observing how modern agriculture has depleted essential nutrients from our food, David developed base One as a science-based solution to bridge this nutritional gap.
"Modern food no longer provides what our cells need. I created base One to give the body exactly what intensive farming has taken away."
For who
Who base One was designed for
6 profiles whose micronutritional needs are structurally documented.
The mentally-overloaded professional
Chronic stress, light sleep, fatigue by 3 PM. Stress burns through magnesium and B vitamins in cascade. base One rebuilds the foundation.
Read article →The 35-50 woman in pre-perimenopause
Changing cycles, fragile sleep, brain fog. A 5-10 year phase that demands coherent micronutritional support.
Read article →The intensive amateur athlete
Long recovery, post-effort fatigue, fragile immunity. base One = foundation. Specialized sport supplements stack on top.
Read article →The exhausted parent
Interrupted sleep, mental load, little time to cook balanced. One spoon a day, easy to integrate.
Read article →The vegetarian or vegan
Active B12, iron (separate), zinc: deficiencies statistically present in 40-50% of vegans. base One addresses 2 of 3.
Read article →The convalescent or post-burnout
Post-infection, post-treatment, recovering from burnout: orthomolecular micronutrition accelerates cellular restoration.
Read article →The elite athlete
High training volume, performance demand. Oxidative stress and depletion in magnesium, B-complex and selenium are structural. base One locks in the micronutrient base.
Read article →Pregnant or breastfeeding
Conception, pregnancy, breastfeeding: needs for 5-MTHF (neural tube), methylcobalamin B12, iodine and magnesium rise significantly. base One covers these documented deficits (validate dosage with your practitioner).
Read article →After a restrictive diet
Weight loss, intermittent fasting, prolonged hypocaloric diet: frequent deficiencies in B-complex, zinc, magnesium, iron. base One rebuilds the foundation without calories.
Read article →nuho Blog
The science behind base One
Powder multivitamin: why 29 actives (and not 50)
Why base One contains 29 compounds and not 50 or 80. Bioavailable forms, clinical dosages, formulated in Switzerland...
Read →Why 30 vitamins in one pill never absorb
Why 30 vitamins in one tablet never absorb. DMT1 antagonisms, cellular neutralizations, molecular competitions: the biochemistry that contradicts...
Read →Cramps, nails, skin: 7 deficiency signs we miss
Night cramps, ridged nails, dry skin, mood swings, light sleep, hair loss, recurring colds: the orthomolecular grid for...
Read →Frequently asked questions about base One
Why is a multivitamin necessary today, even with a balanced diet?
The nutrient density of fruits, vegetables and grains has dropped 20-80% over 85 years depending on the nutrient. A 2025 optimized diet (varied vegetables, oily fish, legumes, seeds) shows deficits of 19-72% compared to a 1940 farmer's day. Documented in CIQUAL ANSES, Mayer 1997/2022 — independent of individual food choices. Targeted supplementation is no longer optional: it has become structural.
Is base One suitable for daily long-term use?
base One is formulated for daily intake. Dosages cover the structural deficits of contemporary diets while staying below EFSA and OSAV tolerable limits. No compound poses a toxic accumulation risk at the recommended dose. During pregnancy, breastfeeding, diagnosed pathology or medication, consult a healthcare professional before supplementation.
Can I combine base One with other supplements (omega-3, vitamin D, iron, zinc)?
Yes, base One fits into a broader protocol. Coherent pairings: omega-3 (EPA/DHA), vitamin D3, coenzyme Q10, polyphenols. Caution with iron: take 4-6 hours apart to avoid DMT1 transporter competition. With added zinc, monitor the zinc/copper balance. With selenium, do not exceed 800 µg/day total.
Why a powder rather than capsules or tablets?
One base One dose = 6 g of actives, equivalent to 12 standard 500 mg capsules. The powder format integrates 29 bioactive compounds at clinical dosages, impossible to achieve in capsules without multiplying units. Water dissolution also favors progressive absorption and concurrent cellular hydration.
Why are iron and calcium deliberately absent from the formula?
Deliberate scientific choice. Iron, zinc, copper and calcium share the DMT1 intestinal transporter. Administered together in solution, they mutually inhibit each other, reducing absorption by 40-80%. Including them would compromise the entire formula. Vitamin C at 580 mg, however, potentiates non-heme dietary iron absorption: a functional response more effective than direct supplementation.
When and how to take base One?
One 6 g dose dissolves in 500 ml of water at room or cool temperature. Best consumed in the morning before or with breakfast. Morning intake optimizes B-vitamin and magnesium availability throughout the day. For digestive sensitivity, take with meals. Avoid hot water to preserve heat-sensitive bioactive forms.
Is base One suitable for vegetarians and vegans?
base One precisely addresses the structural deficits of vegetarian and vegan diets. Vitamin B12 (absent from plants) is provided in its two most bioavailable active forms. Iodine, deficient outside seafood, is covered at 200 µg per dose. Zinc is provided as citrate, high absorption. Vitamin C at 580 mg potentiates non-heme plant iron absorption, functionally compensating for the absence of heme animal iron.
Is base One suitable for athletes and muscle recovery?
Several axes directly relevant in sport context. L-glutamine at 1,500 mg limits muscle catabolism induced by intense effort and supports gut mucosa integrity. Magnesium and potassium regulate muscle contraction and prevent cramps. B vitamins optimize mitochondrial ATP production. Vitamin C and selenium reduce post-exercise oxidative stress.
Is base One suitable for pregnant or breastfeeding women?
base One is particularly suited to conception, pregnancy and breastfeeding phases. Folate as active 5-MTHF is directly assimilable, including for the 30-50% of women with an MTHFR polymorphism: it conditions neural tube closure. Methylcobalamin (B12) supports fetal neurological development. Iodine (200 µg) covers the structural deficit outside seafood. Medical advice remains recommended to personalize the protocol.
How long does it take to feel the effects of base One?
Timeframes vary with starting micronutrient status. People with marked deficits may feel improvement from the first doses (fatigue, mental clarity), thanks to the immediate availability of bioactive forms. For moderate deficits, effects build over 1-2 weeks. Three months is the optimal duration to allow cellular renewal and enzymatic regulation processes to express fully.
Does base One contain sugar, additives or artificial excipients?
base One is free of sugar, maltodextrin and artificial excipients. The three auxiliaries each have a documented function: steviol glycosides (sweet perception, zero glycemic index, ~15 mg/dose); citric acid (pH corrector and divalent mineral absorption potentiator); natural fruit-extracted flavor (palatability without synthetic solvent). No ingredient interferes with active compounds.
What's the difference between base One and a pharmacy multivitamin at 2-9 CHF?
base One is a complete formula of 29 bioactive compounds — vitamins, minerals, amino acids and organic acid — selected on strict orthomolecular criteria and dosed in synergy. Forms are bioactive (5-MTHF, P-5-P, methylcobalamin, magnesium citrate): the cell receives what the label announces. Low-cost supplements generally use poorly bioavailable forms and sub-clinical doses: only a tiny fraction reaches the cell. Swiss manufacturing, batch-level quality controls.
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